Missouri City is located in eastern Fort Bend County with a portion of the city extending north into Harris County. Missouri City is bordered by the city of Houston to the north and east, Stafford to the northwest, Sugar Land to the west, and Arcola to the southeast, as well as unincorporated communities such as Fifth Street to the north, Fresno to the east, and Sienna Plantation to the south. Downtown Houston is 17 mi (27 km) to the northeast. Oyster Creek flows in a southerly direction through the municipality.
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Source: Wikipedia